On Certain Cases in Which the Foramen Ovale was Still Patent in the Adult

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Patent foramen ovale in adult life.

Description and prevalence In the fetus venous blood enters the right atrium and is directed into either the right ventricle (predominantly from the superior vena cava) or the left atrium (predominantly from the inferior vena cava, being guided by the eustachian valve across the foramen ovale). At birth the decrease in pulmonary vascular resistance and increase in systemic vascular resistance c...

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Patent foramen ovale: the jury is still out.

Paradoxical embolism through a patent foramen ovale (PFO) was described first in 1877.1 It was never doubted that this could lead to a stroke. However, it was more than 100 years before it was realized that a PFO is in fact a frequent cause of cerebral embolism and there is a continuous debate as to how these patients should be treated. In 35–40% of all patients with an ischemic stroke the caus...

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Patent Foramen Ovale

The patent foramen ovale (PFO) is a normal interatrial communication during fetal life that persists after birth in approximately 1 of every 4 adults. PFO is a potential route for embolic transit from the systemic venous circulation to the brain. Though there is compelling circumstantial evidence implicating PFO, the precise role of PFO in the pathogenesis of cryptogenic stroke is not yet estab...

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Patent Foramen Ovale

Patent foramen ovale (PFO) is not uncommondit appears in perhaps 10% to 25% of the populationdbut only a small percent of cases will produce any clinical sequelae, such as refractory hypoxia, orthodeoxia-platypnea syndrome, or migraine headaches. PFO is most notorious, however, for its association with paradoxical embolus and cryptogenic stroke (1). Conclusive proof of a causal relationship bet...

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Patent foramen ovale.

Patent foramen ovale (PFO) is a common developmental anomaly that allows for the passage of blood and other substances from the venous to the arterial circulation. The study of PFO closure has been challenging due to widely available off-label closures performed outside the clinical trial setting. To date, no study has demonstrated benefit of closure using intention-to-treat analyses. Secondary...

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ژورنال

عنوان ژورنال: BMJ

سال: 1857

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.s4-1.24.500